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How long does cardarine take to work? (GW 50156)

There’s no doubt about it, if you’re focused on building lean muscle mass, you will have undoubtedly heard about Cardarine GW 501516 by now.

Click here to buy legal Cardarine GW 501516 version >

Whether you’re looking to gain greater insight into Cardarine cycles, or simply want to learn more about taking Cardarine – we’re about to share everything we know about Cardarine GW 501516 – so, let’s get started.

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What is Cardarine GW 501516?

While Cardarine GW 501516 is often marketed as a SARM (selective androgen receptor modulator), it’s actually a PPAR Agonist.

But what does that really mean for Cardarine GW 501516? Here’s what a PPAR Agonist really is:

Peroxisome proliferator-activated receptors (PPARs) are involved in the metabolic regulation of lipid and lipoprotein levels. With animal testing showing positive signs in the treatment of metabolic diseases, studies have shown that it increases endurance during exercise significantly.

So, it’s no real surprise that GW 501516 has been picked up by bodybuilders in order to up their game in the gym.

It’s important to note, however, that since it complicated animals’ health during clinical trials, Cardarine GW 501516 was deemed unsafe way back in 2007. Furthermore, GW 501516 has been added to the prohibited compound list by WADA.

GW-XT SARM (AKA Cardarine GW 501516) has been around for some time now, as a part of a collection of selective androgen receptor modulators (SARMs) used for muscle growth. Although, some prefer to consider Cardarine as a PPARδ agonist drug, rather than a SARM.

What does Cardarine GW 501516 contain?

Cardarine is a synthetic substance made of monocarboxylic acid – most commonly known as Endurobol. While it claims to be an orally active supplement, as a synthetic composition it required a solid exercise routine to allow proper digestion.

How does Cardarine GW 501516 work?

Despite its original intention to treat metabolic diseases and cardiovascular health, Cardarine GW 501516 has quickly been picked up by bodybuilders looking to burn fat, and keep lean muscle during a cutting cycle.

Also Read: Cardarine side effects: GW-501516 Benefits, Uses, Dosage (SARMS)

Cardarine GW 501516 works by looking to bind to PPARδ receptors, a group of proteins found in muscles and fatty acids in the body. When activated, Cardarine GW 501516 encourages your body to burn fat, increase muscle endurance and potentially enhance building lean muscle mass.

While on the topic of selective androgen receptor modulators (SARMs), Cardarine GW 501516 is often mentioned as a common stacking compound.

Much like cutting anabolic steroids, Cardarine GW 501516 has proven to be a reliable fat burner if you’re looking to trim down, lose fat and help boost lean muscle mass. If you currently have a high body fat percentage, many a Cardarine review has shown it to be successful for weight loss.

Here are the main results of Cardarine binding to the PPARδ receptor:

  • Increased oxidative capacity in muscles (which leads to a drop in body fat and increased endurance)
  • Switching our energy source from glucose to fat (suppression of glucose metabolism)

Where did Cardarine come from?

Research scientists began to work on compounds that could increase fat burning and physical endurance in sedentary and overweight adults. This then led them down the PPAR-delta route, researching whether Cardarine GW 501516 could have. positive impact on the many metabolic problems associated with an inactive lifestyle, including:

  • High blood pressure
  • Diabetes
  • Increased inflammation
  • Cardiovascular health

What’s the right dosage of Cardarine GW 501516?

In terms of hitting the right GW 501516 dosage, since Cardarine consumption is unapproved for human use, the correct dosage is a little unknown.

However, many users of Cardarine GW 501516 opt for a dose between 2.5 and 10mg per day, for a cycle of around 12 weeks. While other users looking to burn fat may opt for 10 to 20mg per day.

With potential cancer risks, there is no ‘safe’ dosage.

How long does Cardarine take to work?

In terms of how long it takes for Cardarine GW 501516 to kick in, some users report noticing its effects pretty much right away, even on a 10mg dosage.

Also Read: A Guide to SARMs

Primarily used to burn fat, Cardarine GW 501516, many users report seeing a drop in body fat around 10 to 14 days into a Cardarine cycle. However, they also mention how improved endurance (increased by up to 60%!) was seen within 30 minutes. Crazy, huh?

Cardarine GW 501516 half life

With a half life of approximately 24 hours, SARMs and Cardarine GW 501516 typically remain in your body for some time, before being flushed out of your system.

This means that its half life allows it to stay in your body and function well for this period of time. However, with this half life, comes potential side effects – of both Cardarine GW 501516 and other popular SARMs.

What are the benefits of Cardarine GW 501516?

  • Cardarine GW 501516 may reduce LDL cholesterol (“bad ” cholesterol) which could support heart health
  • By activating the PPARδ receptor, Cardarine GW 501516 could, in turn, produce anti-inflammatory effects, reducing oxidative damage to blood vessels and tissues
  • With the power for improved endurance, Cardarine GW 501516 can keep fitness levels running high
  • Potential to increase lean muscle mass – but this may be enhanced by stacking Cardarine with a SARM (selective androgen receptor modulator)
  • Improved recovery times by enhancing nitric oxide levels in the arteries
  • Cardarine GW 501516 tries to suppress glucose metabolism in the liver, working to switch energy sources from glucose to fatty acids
  • No need for post cycle therapy (in most cases). It can also be used during post cycle therapy after a SARM cycle, to avoid fat gain

With many users choosing GW 501516 for increased endurance, many report experiencing even better endurance week after week, especially during running.

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Cardarine and lowering body fat

The majority of Cardarine GW 501516 users utilize this drug for its power to enhance weight loss, with the aim of reducing body fat percentage to lose weight and reveal lean muscle mass. In a similar way to increased endurance, Cardarine works as a fat burner in two different ways:

  • Increased oxidative capacity in muscles (which means the power to burn more calories)
  • Suppression of Glucose metabolism – switching energy source from Glucose to fatBy switching energy source from glucose to fat, it allows your body to directly burn off fat instead of first burning off the excess glucose that our body stored

Improved cardiovascular health

One of the key reasons for the development and research of GW 501516 – to treat cardiovascular diseases.

During animal studies and testing (on rats) it proved to have a positive impact on our cardiovascular health. Even at low doses, Cardarine showed to clear up blood vessels which lower the risk of heart attack and other cardiovascular diseases.

Of course, there aren’t any human trials to back these claims up for human use.

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Muscle mass

In terms of GW 501516 and its muscle-building abilities, one study (in mice) has shown the activation of PPAR-delta via a Cardarine supplement drove the development of muscle fibers – also improving endurance. While boosting fat loss, it may be able to help preserve muscle mass.

Blood flow

Alongside helping you get stacked, GW 501516 has been shown to improve blood flow and repair wounds. In relation to bodybuilding and rigorous exercise, there is potential for this untested (on humans) drug to help you recover faster.

The conclusion

Put simply, many a Cardarine review have supported Cardarine’s abilities to enhance physical performance, increasing endurance while working as a fat burner. Of course, like any other bodybuilding supplement, there are some side effects to look out for.

Are there any side effects of Cardarine GW 501516?

Known as a research chemical, there is little true research into Cardarine GW 501516. This means that reported side effects are typically reported by users – but this should still give you a good idea of what to expect during Cardarine cycles.

Meanwhile, in one study of 13 men with high belly fat and bad cholesterol levels, Cardarine GW 501516 showed to decrease triglycerides, fatty acids and VLDL proteins.

In an animal study, despite results showing it improved blood circulation in the brain, reducing oxidative damage and stress, it also increased IL-6, which can cause brain cell damage.

Let’s break down the side effects of Cardarine a little more, and investigate why it isn’t deemed fit for human consumption.

Liver damage

It’s surprising how much Cardarine GW 501516 may impact liver health. Much like many other bodybuilding supplements, these need to filter through the liver, however, it can be a lot for the liver to manage – since the liver is the most critical organ involved in the burning, release, and storage of fat in the body.

PPAR-delta is responsible for regulating glucose metabolism, as well as insulin sensitivity – triggering the liver to shift its source of energy from glucose to fatty acids, thereby reducing blood sugar.

Also Read: The Ultimate Alternatives to SARMs

During initial animal and cell studies, Cardarine GW 501516 showed to be potentially beneficial to liver health, however, within a short amount of time, GW 501516 caused the death of liver cells as well as fibrosis or liver damage. This shows that even at potentially low doses, Cardarine can be dangerous to the liver.

Kidney disease and heart health

Researchers have found that this popular research compound (at small doses) decreased tissue damage and inflammation in the arteries and blood vessels of mice. This led them to further investigate the potential of Cardarine reducing heart disease.

In one mice study, researchers found Cardarine was responsible for inhibiting oxidative damage to blood vessels. During this, it was also presumed Cardarine would increase nitric oxide production and as a result, could lower plaque buildup in the arteries.

When added to human heart cells, Cardarine produced an increase in the growth of new blood vessels. While these findings could potentially benefit someone with heart disease, it could be a little overboard for a healthy person, or one who had a propensity of developing cancer.

In the same study, when reviewing Cardarine’s effects on the kidneys, inflammation in the kidneys was reduced followed by an overall lowered activity of genes that indicate the presence of kidney disease. If you ask us, increased endurance isn’t worth the potential for a heart attack, liver damage and other cardiovascular diseases.

Is Cardarine legal?

Cardarine GW 501516 is currently classified as an illegal substance, since it has been deemed unfit for human consumption.

It is currently banned by the World Anti Doping Agency, which means it cannot be used by those looking to compete.

Unfortunately, with no human studies, both low doses and high doses of Cardarin GW 501516 are somewhat a grey area. Of course, as users have claimed, you may experience accelerated fat loss, but with side effects including liver damage, is it worth it?

If you’re looking to buy Cardarine, you may be better opting for a legal, natural alternative, like CARDALEAN.

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Sure, Cardarine may be able to help you lose weight and enhance endurance, but are the benefits worth the potential side effects? We think not.

Plus, with no human trials, it’s scary to use Cardarin GW 501516 without understanding its true potential side effects.

Why not opt for a 100% legal, safer alternative? This is why we created CARDALEAN – a safe, natural alternative to Cardarine – with zero side effects. You can still enjoy one of the best fat burners around, without any concerns for your liver or heart.

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The Brutal Force Team

The Brutal Force Team

We research and write articles about health, fitness and dieting. Each of our articles includes sources from scientific studies where possible.

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The Brutal Force Team

The Brutal Force Team

We research and write articles about health, fitness and dieting. Each of our articles includes sources from scientific studies where possible.